Novox® Cheawable Tablets
(CARPROFEN)
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Non-steroidal anti-inflammatory drug
For oral use in dogs only
CAUTION: Federal law restricts this drug to use by or on
The order of licensed veterinarian.
DOSAGE AND ADMINISTRATION
Always provide Client Information Sheet with prescription. Carefully
consider the potential benefits and risk of Novox and other treatment
options before deciding to use Novox. Use the lowest effective dose
for the shortest duration consistent with individual response.
The recommended dosage for oral administration to dogs is 2 mg/lb of
body weight daily. The total daily dose may be administered as 2 mg/lb
of body weight once daily or divided and administered as 1 mg/lb twice
daily. For the control of postoperative pain, administer approximately
2 hours before the procedure.
Novox chewable tablets are scored and dosage should be calculated in
half-tablet increments. Tablets can be halved by placing the tablet on a
hard surface and pressing down on both sides of the score. These liver
flavored Novox chewable tablets may be offered to the dog by hand or
placed on food. If the dog does not willingly consume the tablets, they
may be hand-administered (pilled) as with other oral tablet medications.
Care should be taken to ensure that the dog consumes the complete
dose.
HOW SUPPLIED
Novox chewable tablets are scored, and contain 25 mg, 75 mg or
100 mg of carprofen per tablet. Each tablet size is packaged in bottles
containing 30,60 or 180 tablets.
EFFECTIVENESS
Confirmation of the effectiveness of carprofen for the relief of pain and
inflammation associated with osteoarthritis, and for the control of
postoperative pain associated with soft tissue and orthopedic surgeries,
was demonstrated in 5 placebo-controlled, masked studies examining
the anti-inflammatory and analgesic effectiveness of carprofen caplets in
various breeds of dogs. Separate placebo-controlled, masked, multicenter
field studies confirmed the anti-inflammatory and analgesic effectiveness
of carprofen caplets when dosed at 2 mg/lb once daily or when divided
and administered at 1 mg/lb twice daily. In these 2 field studies, dogs
diagnosed with osteoarthritis showed statistically significant overall
improvement based on lameness evaluations by the veterinarian and
owner observations when administered carprofen at labeled doses.
Separate placebo-controlled, masked, multicenter field studies confirmed
the effectiveness of carprofen caplets for the control of postoperative
pain when dosed at 2 mg/lb once daily in various breeds of dogs.
In these studies, dogs presented for ovariohysterectomy, cruciate repair
and aural surgeries were administered carprofen preoperatively and for
a maximum of 3 days (soft tissue) or 4 days (orthopedic) postoperatively.
In general, dogs administered carprofen showed statistically significant
reduction in pain scores compared to controls.
ANIMAL SAFETY
Laboratory studies in unanesthetized dogs and clinical field studies have
demonstrated that carprofen is well tolerated in dogs after oral
administration. In target animal safety studies, carprofen was administered
orally to healthy Beagle dogs at 1,3, and 5 mg/lb twice daily (1,3,
and 5 times the recommended total daily dose) for 42 consecutive days
with no significant adverse reactions.
Please refer to the Novox® Chewable Tablets package insert for more
specific information.